Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KHK | P50053 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18694232 | 0.94 | KDM4E (0.59) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL18694396 | 0.89 | HPGD (0.60) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL18717651 | 0.87 | KDM4E (0.56) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL18694144 | 0.86 | KHK (0.56) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL18694794 | 0.85 | KDM4E (0.51) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL18694424 | 0.82 | CFTR (0.55) | KDM4EHSD17B10HPGDALDH1A1CFTR | |
| SCHEMBL18692826 | 0.77 | KMT2A (0.57) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL18694035 | 0.77 | KDM4E (0.51) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL18694031 | 0.77 | CFTR (0.59) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL18694078 | 0.77 | KDM4E (0.61) | KDM4EHSD17B10HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017060873-A1 | SUBSTITUTED PYRAZOLO[3,4-B]PYRIDIN-6-CARBOXYLIC ACIDS AND THEIR USE | AbbVie S.à.r.l. (LU) | 2017-04-13 | — | — | WO | disclosed |