Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 1/20 | 0.31 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.31 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.31 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17789025 | 0.87 | EZH2 (0.33) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL18743893 | 0.83 | EZH2 (0.31) | EZH2 | |
| SCHEMBL17792510 | 0.82 | EZH2 (0.36) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL18743904 | 0.78 | DAO (0.32) | — | |
| SCHEMBL18743926 | 0.78 | — | — | |
| SCHEMBL18743898 | 0.76 | DAO (0.43) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL17789023 | 0.70 | KDM4E (0.34) | EZH2 | |
| SCHEMBL18744464 | 0.68 | KDM4E (0.33) | — | |
| SCHEMBL17789037 | 0.67 | DRD4 (0.34) | — | |
| SCHEMBL18743903 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624205-B2 | Substituted 6,5-fused bicyclic heteroaryl compounds | Epizyme, Inc. (US) | 2017-04-18 | — | — | US | disclosed |