Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17789024 | 0.87 | DHODH (0.35) | DHODH | |
| SCHEMBL17792498 | 0.82 | DHODH (0.37) | DHODH | |
| SCHEMBL19934961 | 0.80 | CYP1A2 (0.36) | DHODH | |
| SCHEMBL18743895 | 0.77 | PIK3CD (0.32) | — | |
| SCHEMBL18743913 | 0.74 | — | — | |
| SCHEMBL18743932 | 0.71 | EZH2 (0.33) | — | |
| SCHEMBL18743917 | 0.69 | — | — | |
| SCHEMBL18743923 | 0.69 | — | — | |
| SCHEMBL18743912 | 0.68 | — | — | |
| SCHEMBL19390935 | 0.68 | EZH2 (0.38) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624205-B2 | Substituted 6,5-fused bicyclic heteroaryl compounds | Epizyme, Inc. (US) | 2017-04-18 | — | — | US | disclosed |