Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A1 | O00337 | 1/20 | 0.41 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.41 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.41 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.41 |
| ▸ | P2RY2 | P41231 | 11/20 | 0.37 |
| ▸ | P2RY6 | Q15077 | 7/20 | 0.37 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17972446 | 0.86 | P2RY14 (0.35) | P2RY2P2RY6P2RY4 | |
| SCHEMBL17972448 | 0.83 | SLC28A1 (0.39) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL18744090 | 0.81 | SLC28A1 (0.41) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL19534593 | 0.81 | SLC28A1 (0.43) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL18464130 | 0.79 | SLC28A1 (0.39) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL19534460 | 0.77 | STING1 (0.53) | SLC28A1SLC28A2SLC29A1SLC28A3STING1 | |
| SCHEMBL14946357 | 0.76 | SLC28A1 (0.37) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL20056902 | 0.74 | STING1 (0.38) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL25400489 | 0.74 | SLC28A1 (0.35) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL12170354 | 0.74 | SLC28A1 (0.35) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624249-B2 | Nucleoside kinase bypass compositions and methods | MERCK SHARP & DOHME CORP. (US) | 2017-04-18 | — | — | US | disclosed |