Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.50 |
| ▸ | HINT1 | P49773 | 3/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | ADA | P00813 | 1/20 | 0.45 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 2/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.43 |
| ▸ | KRAS | P01116 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15045902 | 0.90 | ADORA2A (0.52) | ADORA2AHINT1NT5EHPGDPOLB | |
| SCHEMBL15259226 | 0.90 | ADORA2A (0.52) | ADORA2AHINT1NT5EHPGDPOLB | |
| 2'-B-Methyl-Guanosine SCHEMBL474745 | 0.87 | ADORA2A (0.65) | ADORA2AHINT1NT5EHPGDADORA3 | |
| 2'-B-Methyl-Guanosine SCHEMBL21007207 | 0.87 | ADORA2A (0.65) | ADORA2AHINT1NT5EHPGDADORA3 | |
| 2'-B-Methyl-Guanosine SCHEMBL15187539 | 0.87 | ADORA2A (0.65) | ADORA2AHINT1NT5EHPGDADORA3 | |
| 2'-B-Methyl-Guanosine SCHEMBL10819882 | 0.87 | ADORA2A (0.65) | ADORA2AHINT1NT5EHPGDADORA3 | |
| 2'-B-Methyl-Guanosine SCHEMBL14946249 | 0.87 | ADORA2A (0.65) | ADORA2AHINT1NT5EHPGDADORA3 | |
| 2'-B-Methyl-Guanosine SCHEMBL12149502 | 0.87 | ADORA2A (0.65) | ADORA2AHINT1NT5EHPGDADORA3 | |
| 2'-B-Methyl-Guanosine SCHEMBL10208618 | 0.87 | ADORA2A (0.65) | ADORA2AHINT1NT5EHPGDADORA3 | |
| 2'-B-Methyl-Guanosine SCHEMBL18537403 | 0.87 | ADORA2A (0.65) | ADORA2AHINT1NT5EHPGDADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624249-B2 | Nucleoside kinase bypass compositions and methods | MERCK SHARP & DOHME CORP. (US) | 2017-04-18 | — | — | US | disclosed |