Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 14/20 | 0.80 |
| ▸ | LMNA | P02545 | 2/20 | 0.80 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.80 |
| ▸ | GMNN | O75496 | 1/20 | 0.80 |
| ▸ | BLM | P54132 | 1/20 | 0.80 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.80 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.80 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.79 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23747296 | 0.91 | STING1 (0.81) | STING1LMNARAPGEF3KMT2AGMNN | |
| SCHEMBL24601699 | 0.91 | STING1 (0.69) | STING1LMNARAPGEF3KMT2AGMNN | |
| Cyclic Adenosine Monophosphate SCHEMBL23829820 | 0.89 | STING1 (1.00) | STING1LMNARAPGEF3KMT2AGMNN | |
| Cyclic Adenosine Monophosphate SCHEMBL20912149 | 0.89 | STING1 (1.00) | STING1LMNARAPGEF3KMT2AGMNN | |
| Cyclic Adenosine Monophosphate SCHEMBL18311520 | 0.89 | STING1 (1.00) | STING1LMNARAPGEF3KMT2AGMNN | |
| Cyclic Adenosine Monophosphate SCHEMBL23829670 | 0.89 | STING1 (1.00) | STING1LMNARAPGEF3KMT2AGMNN | |
| Cyclic Adenosine Monophosphate SCHEMBL23829591 | 0.89 | STING1 (1.00) | STING1LMNARAPGEF3KMT2AGMNN | |
| Cyclic Adenosine Monophosphate SCHEMBL23829653 | 0.89 | STING1 (1.00) | STING1LMNARAPGEF3KMT2AGMNN | |
| SCHEMBL22434642 | 0.89 | STING1 (1.00) | STING1LMNARAPGEF3KMT2AGMNN | |
| Cyclic Adenosine Monophosphate SCHEMBL23829673 | 0.89 | STING1 (1.00) | STING1LMNARAPGEF3KMT2AGMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624249-B2 | Nucleoside kinase bypass compositions and methods | MERCK SHARP & DOHME CORP. (US) | 2017-04-18 | — | — | US | disclosed |