SCHEMBL18745

SCHEMBL18745

O=C(O)c1c(-c2cnc3ccccc3c2C(=O)O)cnc2ccccc12

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 4/20 0.51
DHODH Q02127 4/20 0.49
LMNA P02545 1/20 0.49
TSHR P16473 1/20 0.47
ALDH1A1 P00352 3/20 0.47
HPGD P15428 2/20 0.47
HSD17B10 Q99714 2/20 0.47
ALOX15 P16050 1/20 0.47
KMT2A Q03164 3/20 0.46
KDM4E B2RXH2 3/20 0.45
MEN1 O00255 2/20 0.45
MGAM O43451 1/20 0.44
CYP2C19 P33261 2/20 0.44
CYP2D6 P10635 1/20 0.44
GPR3 P46089 1/20 0.44
ERN1 O75460 1/20 0.43
CYP1A2 P05177 1/20 0.42
GLA P06280 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4347338 0.91 DHODH (0.53) PDE10ADHODHLMNATSHRALDH1A1
SCHEMBL3786796 0.85 DHODH (0.48) PDE10ADHODHLMNATSHRALDH1A1
SCHEMBL2512893 0.85 KDM4E (0.60) PDE10ADHODHLMNAALDH1A1HPGD
SCHEMBL352547 0.83 PDE10A (0.50) PDE10ADHODHLMNATSHRALDH1A1
SCHEMBL29450068 0.83 PDE10A (0.50) PDE10ADHODHLMNATSHRALDH1A1
SCHEMBL1759028 0.83 ERN1 (0.54) PDE10ADHODHLMNATSHRALDH1A1
SCHEMBL24338810 0.81 PDE10A (0.49) PDE10ADHODHLMNATSHRALDH1A1
SCHEMBL10466393 0.81 KMT2A (0.51) PDE10ADHODHLMNATSHRALDH1A1
SCHEMBL5759350 0.81 PDE10A (0.57) PDE10ADHODHLMNATSHRALDH1A1
SCHEMBL3502769 0.81 KDM4E (0.41) PDE10ADHODHLMNATSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 23664 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026105085-A1 HYGIENE MONITORING DEVICE, ELECTRONIC OPTICAL READER APPARATUS AND RELATED METHOD TERRAGENE S.A. (UY) 2026-05-21 WO claimed
EP-4698205-A1 PHARMACEUTICAL FORMULATIONS FOR LONGEVITY IN MAMMALS Cellular Longevity, Inc. (US) 2026-02-25 EP claimed
US-12558379-B2 Compositions and methods relating to pooled fetal support tissue BIOTISSUE HOLDINGS INC. (US) 2026-02-24 US claimed
EP-4677363-A1 TUMOR RESIDENT PROTEIN MARKER PANEL FOR PREDICTING RECURRENCE IN BILE DUCT CANCER PATIENTS Albert-Ludwigs-Universität Freiburg Körperschaft des öffentlichen Rechts (DE) 2026-01-14 EP claimed
US-20260008809-A1 PROTEIN PURIFICATION NUCLERA LTD (GB) 2026-01-08 US claimed
US-12510545-B2 Method and composition for rapid detection of protein soils ECOLAB USA INC. (US) 2025-12-30 US claimed
WO-2025244838-A1 IMPROVED COLLAGEN COATINGS CORNING INCORPORATED (US) 2025-11-27 WO claimed
US-20250327818-A1 SULCUS-PROTEINS FOR THE DETECTION OF PERI-IMPLANTITIS ALBERT LUDWIGS UNIV FREIBURG KOERPERSCHAFT DES OEFFENTLICHEN RECHTS (DE) 2025-10-23 US claimed
EP-4211456-B1 ZINC AND COPPER MEASUREMENT HACH CO (US) 2025-10-15 EP claimed
US-20250275536-A1 Antimicrobial Composition KAMER, Patrick (CH) 2025-09-04 US claimed
US-5506144-A SEPARATING NON-GLYCATED PROTEINS BY PRECIPITATION, CONTRACTING WITH SIGNAL FORMING AGENT SPECIFIC FOR GLYCATED PROTEIN AXIS BIOCHEMICALS AS (NO) 1996-04-09 US claimed
US-5491093-A Quantitative determination of lipid, and of co-existing two compounds CANON KABUSHIKI KAISHA (JP) 1996-02-13 US claimed
US-5443981-A Membrane fraction from leaf sheath tissue of grass species RUTGERS, THE STATE UNIVERSITY (US) 1995-08-22 US claimed
EP-0557350-B1 ASSAY FOR GLYCATED BLOOD PROTEINS AXIS BIOCHEMICALS AS (NO) 1994-10-05 EP claimed
WO-1994007911-A1 METHOD AND KIT FOR ISOLATION AND PURIFICATION OF ENZYME-ANTIBODY CONJUGATES PIERCE CHEMICAL COMPANY (US) 1994-04-14 WO claimed
US-5266686-A Method for isolation and purification of enzyme-antibody conjugates PIERCE CHEMICAL COMPANY (US) 1993-11-30 US claimed
EP-0557350-A1 ASSAY FOR GLYCATED BLOOD PROTEINS. AXIS RESEARCH (NO) 1993-09-01 EP claimed
EP-0531933-A2 Quantitative determination of liquids, pure or complexed with other components CANON KABUSHIKI KAISHA (JP) 1993-03-17 EP claimed
WO-1992008984-A1 ASSAY FOR GLYCATED BLOOD PROTEINS AXIS RESEARCH AS (NO) 1992-05-29 WO claimed
US-4839295-A Measurement of protein using bicinchoninic acid PIERCE CHEMICAL COMPANY (US) 1989-06-13 US claimed