Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | TTK | P33981 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DDO | Q99489 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | TEK | Q02763 | 1/20 | 0.38 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21118153 | 0.82 | ATM (0.44) | CYP11B2CYP11B1AURKATTKAURKB | |
| SCHEMBL30337602 | 0.82 | CYP11B1 (0.55) | DYRK1BCYP11B2CYP11B1MEN1KDM4E | |
| SCHEMBL13500322 | 0.81 | MAP4K4 (0.55) | DYRK1BCYP11B2CYP11B1MEN1KDM4E | |
| SCHEMBL16606293 | 0.78 | ATM (0.50) | CYP11B2CYP11B1AURKATTKAURKB | |
| SCHEMBL31290743 | 0.78 | ATM (0.61) | CYP11B2CYP11B1AURKATTKAURKB | |
| SCHEMBL4152091 | 0.76 | NTRK1 (0.55) | DYRK1BCYP11B2CYP11B1AURKATTK | |
| SCHEMBL558114 | 0.76 | DYRK1B (0.54) | DYRK1BCYP11B2CYP11B1ATMMEN1 | |
| SCHEMBL633420 | 0.75 | MEN1 (0.68) | CYP11B2CYP11B1ATMMEN1CYP2A6 | |
| SCHEMBL187404 | 0.74 | — | — | |
| SCHEMBL97781 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624193-B2 | Cyclic azine derivatives, processes for producing these, and organic electroluminescent element containing these as component | TOSOH CORPORATION (JP) | 2017-04-18 | — | — | US | disclosed |