Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 9/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663344 | 0.90 | MAOB (0.56) | MAOBMAPTSMN1; SMN2TNIKRAB9A | |
| SCHEMBL1666463 | 0.90 | MAPT (0.52) | MAOBMAPTSMN1; SMN2KDM4EHPGD | |
| SCHEMBL1664927 | 0.89 | TNIK (0.44) | MAOBMAPTSMN1; SMN2KDM4EHPGD | |
| SCHEMBL8771269 | 0.89 | MAOB (0.47) | MAOBMAPTSMN1; SMN2KDM4EHPGD | |
| SCHEMBL1665026 | 0.89 | MAOB (0.43) | MAOBMAPTSMN1; SMN2KDM4EHPGD | |
| SCHEMBL1665595 | 0.89 | ABL1 (0.48) | MAOBMAPTSMN1; SMN2KDM4EHPGD | |
| SCHEMBL6126511 | 0.89 | MAOB (0.46) | MAOBMAPTSMN1; SMN2KDM4EHPGD | |
| SCHEMBL1664559 | 0.89 | ABL1 (0.48) | MAOBMAPTSMN1; SMN2KDM4EHPGD | |
| SCHEMBL1664478 | 0.89 | MAOB (0.46) | MAOBMAPTSMN1; SMN2KDM4EHPGD | |
| SCHEMBL1663848 | 0.89 | TNIK (0.47) | MAOBMAPTSMN1; SMN2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9622991-B2 | Hematopoietic growth factor mimetic small molecule compounds and their uses | LIGAND PHARMACEUTICALS INC. (US) | 2017-04-18 | — | — | US | disclosed |