Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18749777 | 0.90 | MRGPRX4 (0.50) | MRGPRX4FFAR1LMNAMAPTCD274 | |
| SCHEMBL18749814 | 0.89 | MRGPRX4 (0.49) | MRGPRX4FFAR1LMNAMAPTCD274 | |
| SCHEMBL18749558 | 0.89 | MRGPRX4 (0.49) | MRGPRX4FFAR1LMNAMAPTCD274 | |
| SCHEMBL18749766 | 0.89 | MRGPRX4 (0.46) | MRGPRX4LMNAMAPTALDH1A1MAPK1 | |
| SCHEMBL18749833 | 0.88 | PTGER1 (0.39) | MRGPRX4PTGS2MAPTL3MBTL1LTB4R | |
| SCHEMBL18749689 | 0.88 | MRGPRX4 (0.48) | MRGPRX4FFAR1LMNAMAPTCD274 | |
| SCHEMBL18749796 | 0.88 | MRGPRX4 (0.37) | MRGPRX4PTGS2LMNAMAPTCD274 | |
| SCHEMBL18749430 | 0.88 | MRGPRX4 (0.48) | MRGPRX4PTGS2FFAR1LMNAMAPT | |
| SCHEMBL18515140 | 0.87 | CD274 (0.40) | MRGPRX4LMNACD274ALDH1A1MAPK1 | |
| SCHEMBL18749817 | 0.87 | MRGPRX4 (0.47) | MRGPRX4FFAR1MAPTCD274ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9907307-B2 | Aromatic compound and uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-03-06 | — | — | US | disclosed |
| US-9788547-B2 | Aromatic compound and uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-10-17 | — | — | US | disclosed |
| US-20170105413-A1 | AROMATIC COMPOUND AND USES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-04-20 | — | — | US | disclosed |
| US-20170105416-A1 | AROMATIC COMPOUND AND USES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170105413-A1 | AROMATIC COMPOUND AND USES THEREOF | TYR, H1-3, H1-0 | MRGPRX4 959/4885PTGS2 4781/4885FFAR1 3450/4885 |
| US-20170105416-A1 | AROMATIC COMPOUND AND USES THEREOF | TYR, H1-3, H1-10 | MRGPRX4 778/4885PTGS2 3985/4885FFAR1 3287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.