Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18515152 | 0.93 | CD274 (0.38) | PTGDR2CD274NPSR1MAPTFFAR4 | |
| SCHEMBL18749585 | 0.88 | MRGPRX4 (0.45) | CD274MAPTRAB9AFFAR4FFAR1 | |
| SCHEMBL18749615 | 0.87 | PTGDR2 (0.39) | PTGDR2CD274NPSR1MAPTRAB9A | |
| SCHEMBL18749471 | 0.86 | MAPT (0.39) | PTGDR2CD274NPSR1MAPTRAB9A | |
| SCHEMBL18514359 | 0.85 | CD274 (0.48) | CD274FFAR4FFAR1 | |
| SCHEMBL18749468 | 0.84 | MAPT (0.37) | PTGDR2CD274NPSR1MAPTRAB9A | |
| SCHEMBL18749427 | 0.84 | SLC22A12 (0.44) | NPSR1MAPTRAB9AALDH1A1HSD17B10 | |
| SCHEMBL18749459 | 0.84 | PTGDR2 (0.39) | PTGDR2CD274NPSR1MAPTRAB9A | |
| SCHEMBL18751145 | 0.84 | MAPT (0.40) | PTGDR2CD274NPSR1MAPTRAB9A | |
| SCHEMBL18749465 | 0.81 | MAPT (0.39) | NPSR1MAPTRAB9AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9907307-B2 | Aromatic compound and uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-03-06 | — | — | US | disclosed |
| US-9788547-B2 | Aromatic compound and uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-10-17 | — | — | US | disclosed |
| US-20170105416-A1 | AROMATIC COMPOUND AND USES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-04-20 | — | — | US | disclosed |
| US-20170105413-A1 | AROMATIC COMPOUND AND USES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170105413-A1 | AROMATIC COMPOUND AND USES THEREOF | TYR, H1-3, H1-0 | PTGDR2 4722/4885CD274 2684/4885NPSR1 1960/4885 |
| US-20170105416-A1 | AROMATIC COMPOUND AND USES THEREOF | TYR, H1-3, H1-10 | PTGDR2 3545/4885CD274 2976/4885NPSR1 2148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.