SCHEMBL1875112

SCHEMBL1875112

C1=CC2=CN=NC2=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27408768 0.97
SCHEMBL4553323 0.69
SCHEMBL13740193 0.67
SCHEMBL14249193 0.67
SCHEMBL219146 0.62
SCHEMBL8973287 0.61
SCHEMBL29615421 0.59
SCHEMBL5376674 0.59
SCHEMBL26292 0.58
SCHEMBL1827788 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116675675-A Preparation method of lenacipam intermediate compound serving as AIDS treatment drug 北京康立生医药技术开发有限公司 2023-09-01 CN claimed
EP-4017853-A1 HETEROCYCLIC PYRAZOLE DERIVATIVES AS TYPE III RECEPTOR TYROSINE KINASE INHIBITORS Development Center for Biotechnology (TW) 2022-06-29 EP claimed
EP-0278603-B1 CONDENSED PYRAZOLE DERIVATIVES AND PROCESS FOR THEIR PREPARATION FARMITALIA CARLO ERBA S.r.l. (IT) 1992-12-02 EP claimed
WO-1986007357-A3 CYCLOPENTAPYRAZOLE AND TETRAHYDROINDAZOLE COMPOUNDS THE UPJOHN COMPANY (US) 1987-04-23 WO claimed
CN-116854630-B Methods and intermediates for preparing therapeutic compounds useful in the treatment of retroviral infections 吉利德科学公司 2026-05-19 CN disclosed
US-12590125-B2 Peptide inhibitors for the inhibition of HIV capsid THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2026-03-31 US disclosed
WO-2025226510-A1 LPAR1 INHIBITORS ABBVIE INC. (US) 2025-10-30 WO disclosed
US-12331056-B2 SHP2 phosphatase inhibitors and methods of use thereof RELAY THERAPEUTICS, INC. (US) 2025-06-17 US disclosed
CN-120078775-A Capsid inhibitors for the treatment of HIV 吉利德科学公司 2025-06-03 CN disclosed
CN-120053446-A Capsid inhibitors for the treatment of HIV 吉利德科学公司 2025-05-30 CN disclosed
CN-120053445-A Capsid inhibitors for the treatment of HIV 吉利德科学公司 2025-05-30 CN disclosed
CN-120053447-A Capsid inhibitors for the treatment of HIV 吉利德科学公司 2025-05-30 CN disclosed
EP-0370955-A1 Herbicidally active N-phenyl azoles CIBA-GEIGY AG (CH) 1990-05-30 EP disclosed
US-4851425-A Cyclopentapyrazole and tetrahydroindazole compounds and their use as anti-inflammatory and anti-allergic agents THE UPJOHN COMPANY (US) 1989-07-25 US disclosed
US-4851425-A Cyclopentapyrazole and tetrahydroindazole compounds and their use as anti-inflammatory and anti-allergic agents THE UPJOHN COMPANY (US) 1989-07-25 US disclosed
US-4851425-A Cyclopentapyrazole and tetrahydroindazole compounds and their use as anti-inflammatory and anti-allergic agents THE UPJOHN COMPANY (US) 1989-07-25 US disclosed
EP-0226624-A1 CYCLOPENTAPYRAZOLE AND TETRAHYDROINDAZOLE COMPOUNDS THE UPJOHN COMPANY (US) 1987-07-01 EP disclosed
WO-1986007357-A3 CYCLOPENTAPYRAZOLE AND TETRAHYDROINDAZOLE COMPOUNDS THE UPJOHN COMPANY (US) 1987-04-23 WO disclosed
WO-1986007357-A3 CYCLOPENTAPYRAZOLE AND TETRAHYDROINDAZOLE COMPOUNDS THE UPJOHN COMPANY (US) 1987-04-23 WO disclosed
WO-1986007357-A2 CYCLOPENTAPYRAZOLE AND TETRAHYDROINDAZOLE COMPOUNDS UPJOHN CO (US) 1986-12-18 WO disclosed