Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C8 | P10632 | 6/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12447856 | 0.87 | KCNH2 (0.60) | CYP2C8KCNH2CYP3A4NR1I2 | |
| SCHEMBL144283 | 0.85 | CYP2C8 (0.55) | CYP2C8KCNH2CYP3A4NR1I2 | |
| SCHEMBL10242549 | 0.85 | CYP2C8 (0.55) | CYP2C8KCNH2CYP3A4NR1I2 | |
| SCHEMBL18752213 | 0.85 | CYP2C8 (0.55) | CYP2C8KCNH2CYP3A4NR1I2 | |
| SCHEMBL2140297 | 0.84 | CYP2C8 (0.54) | CYP2C8KCNH2CYP3A4NR1I2 | |
| SCHEMBL19401365 | 0.83 | MEN1 (0.34) | CYP2C8KCNH2 | |
| SCHEMBL19401315 | 0.80 | KCNH2 (0.54) | CYP2C8KCNH2CYP3A4NR1I2 | |
| SCHEMBL12447846 | 0.78 | CYP2C8 (0.52) | CYP2C8KCNH2CYP3A4NR1I2 | |
| SCHEMBL1918982 | 0.77 | KCNH2 (0.52) | CYP2C8KCNH2 | |
| SCHEMBL10242360 | 0.77 | CYP2C8 (0.58) | CYP2C8KCNH2CYP3A4NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017165233-A1 | BENZOFURAN DERIVATIVES FOR THE TREATMENT OF HEPATITIS C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-28 | — | — | WO | disclosed |
| EP-2545051-B1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | BRISTOL MYERS SQUIBB CO (US) | 2017-04-19 | — | — | EP | disclosed |