Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16247125 | 0.89 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL18752184 | 0.82 | KLKB1 (0.65) | KLKB1 | |
| SCHEMBL17693889 | 0.82 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL21180324 | 0.80 | KLKB1 (0.74) | KLKB1 | |
| SCHEMBL17696322 | 0.78 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL21177966 | 0.78 | KLKB1 (0.71) | KLKB1 | |
| SCHEMBL18725266 | 0.77 | KLKB1 (0.76) | KLKB1 | |
| SCHEMBL17685624 | 0.76 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL17693887 | 0.76 | KLKB1 (1.00) | KLKB1 | |
| Hydrochloric Acid SCHEMBL16247025 | 0.76 | KLKB1 (0.98) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305778-B1 | INHIBITORS OF PLASMA KALLIKREIN | KALVISTA PHARMACEUTICALS LTD (GB) | 2022-01-19 | — | — | EP | disclosed |
| EP-3305778-A1 | INHIBITORS OF PLASMA KALLIKREIN | Kalvista Pharmaceuticals Limited (GB) | 2018-04-11 | — | — | EP | disclosed |
| EP-2999697-B1 | HETEROCYCLIC DERIVATES | KALVISTA PHARMACEUTICALS LTD (GB) | 2017-04-19 | — | — | EP | disclosed |