Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16014012 | 0.87 | — | — | |
| SCHEMBL18755079 | 0.78 | JAK2 (0.53) | JAK2 | |
| SCHEMBL18755088 | 0.78 | JAK2 (0.53) | JAK2 | |
| SCHEMBL18755237 | 0.77 | JAK2 (0.58) | JAK2GAAMAPTGFER | |
| SCHEMBL18856585 | 0.75 | JAK2 (0.73) | JAK2GAAMAPTGFER | |
| SCHEMBL18754968 | 0.74 | JAK2 (0.53) | JAK2 | |
| SCHEMBL18723759 | 0.73 | JAK2 (0.55) | JAK2GAAMAPTGFER | |
| SCHEMBL18755097 | 0.73 | JAK2 (0.62) | JAK2 | |
| SCHEMBL18755108 | 0.72 | JAK2 (0.58) | JAK2GAAGFER | |
| SCHEMBL18755121 | 0.72 | JAK2 (0.60) | JAK2GAAMAPTGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964633-B1 | ANTIVIRAL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2017-04-19 | — | — | EP | disclosed |