Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | IAPP | P10997 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13479126 | 1.00 | GLA (0.38) | GLATDP1MAPTLMNAIAPP | |
| SCHEMBL452002 | 0.82 | HCAR2 (0.38) | GLATDP1MAPTLMNAMEN1 | |
| SCHEMBL22779641 | 0.81 | CCNC (0.31) | — | |
| SCHEMBL15364319 | 0.80 | CA12 (0.42) | MAPTMEN1ALDH1A1KMT2AHTT | |
| SCHEMBL16844231 | 0.78 | HDAC1 (0.33) | — | |
| SCHEMBL23653647 | 0.76 | CA12 (0.46) | MAPTLMNAALDH1A1 | |
| SCHEMBL8072668 | 0.75 | KMT2A (0.35) | MAPTMEN1KMT2A | |
| SCHEMBL21531398 | 0.73 | MEN1 (0.35) | TDP1MEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL21531396 | 0.73 | MEN1 (0.35) | TDP1MEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL18648890 | 0.73 | CYP2C9 (0.59) | GLATDP1MAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3156058-A1 | ANTI-TUMOR PHARMACEUTICAL APPLICATION OF PENTACYCLIC TRITERPENE SAPONIN COMPOUNDS OF SZECHUAN MELANDIUM ROOT | Wang, Xueyong (CN) | 2017-04-19 | — | — | EP | disclosed |