Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 18/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18756178 | 0.91 | CHRM1 (0.52) | CHRM1 | |
| SCHEMBL18756010 | 0.88 | CHRM1 (0.54) | CHRM1 | |
| SCHEMBL18756057 | 0.84 | CHRM1 (0.52) | CHRM1 | |
| SCHEMBL18725500 | 0.83 | CHRM1 (0.73) | CHRM1 | |
| SCHEMBL18756029 | 0.81 | CHRM1 (0.51) | CHRM1 | |
| SCHEMBL17440051 | 0.81 | CHRM1 (0.81) | CHRM1 | |
| SCHEMBL17439993 | 0.81 | CHRM1 (0.81) | CHRM1 | |
| SCHEMBL21235333 | 0.80 | CHRM1 (0.57) | CHRM1 | |
| SCHEMBL18756671 | 0.80 | CHRM1 (0.68) | CHRM1 | |
| SCHEMBL18756673 | 0.80 | CHRM1 (0.57) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3156397-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2019-08-07 | — | — | EP | disclosed |
| EP-3156397-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2017-04-19 | — | — | EP | disclosed |