Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 17/20 | 0.81 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.44 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.44 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.44 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.44 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17440152 | 0.93 | CHRM1 (0.75) | CHRM1 | |
| SCHEMBL17440154 | 0.93 | CHRM1 (0.75) | CHRM1 | |
| SCHEMBL17440113 | 0.92 | CHRM1 (0.78) | CHRM1 | |
| SCHEMBL17440125 | 0.89 | CHRM1 (1.00) | CHRM1 | |
| SCHEMBL18725485 | 0.89 | CHRM1 (1.00) | CHRM1 | |
| SCHEMBL17440025 | 0.89 | CHRM1 (1.00) | CHRM1 | |
| SCHEMBL17440160 | 0.89 | CHRM1 (0.70) | CHRM1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL17440161 | 0.89 | CHRM1 (0.70) | CHRM1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL17440010 | 0.88 | CHRM1 (0.69) | CHRM1 | |
| SCHEMBL18756540 | 0.88 | CHRM1 (0.98) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3156397-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2019-08-07 | — | — | EP | disclosed |
| EP-3156397-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2017-04-19 | — | — | EP | disclosed |