Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 15/20 | 0.48 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18756112 | 0.90 | CHRM1 (0.48) | CHRM1 | |
| SCHEMBL21235168 | 0.89 | CHRM1 (0.47) | CHRM1PDE2APDE11A | |
| SCHEMBL18756357 | 0.89 | CHRM1 (0.49) | CHRM1PDE2APDE11A | |
| SCHEMBL18756158 | 0.85 | CHRM1 (0.48) | CHRM1PDE2APDE11A | |
| SCHEMBL21235159 | 0.85 | CHRM1 (0.48) | CHRM1PDE2APDE11A | |
| SCHEMBL18756633 | 0.85 | CHRM1 (0.49) | CHRM1PDE2APDE11A | |
| SCHEMBL18725443 | 0.82 | CHRM1 (0.63) | CHRM1PDE2APDE11A | |
| SCHEMBL21235440 | 0.79 | CHRM1 (0.48) | CHRM1 | |
| SCHEMBL21235424 | 0.79 | CHRM1 (0.49) | CHRM1 | |
| SCHEMBL18756167 | 0.79 | CHRM1 (0.49) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3156397-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2017-04-19 | — | — | EP | disclosed |