SCHEMBL18758

SCHEMBL18758

O=C(O)c1ccc2cc(C(=O)O)ccc2c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.68
TSHR P16473 2/20 0.61
TP53 P04637 1/20 0.61
CA12 O43570 2/20 0.56
CA1 P00915 2/20 0.56
CA2 P00918 2/20 0.56
CA4 P22748 2/20 0.56
CA6 P23280 2/20 0.56
CA7 P43166 2/20 0.56
CA9 Q16790 2/20 0.56
CA14 Q9ULX7 2/20 0.56
POLB P06746 1/20 0.56
GAA P10253 1/20 0.56
MAPT P10636 1/20 0.56
PTGS2 P35354 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
ALDH1A1 P00352 1/20 0.56
HPGD P15428 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29594563 1.00 KDM4E (0.68) KDM4ETSHRTP53CA12CA1
SCHEMBL29359975 1.00 KDM4E (0.68) KDM4ETSHRTP53CA12CA1
SCHEMBL6916181 1.00 KDM4E (0.68) KDM4ETSHRTP53CA12CA1
Hydrochloric Acid SCHEMBL1681545 0.97 KDM4E (0.65) KDM4ETSHRTP53CA12CA1
Bicarbonate SCHEMBL6557215 0.97 KDM4E (0.65) KDM4ETSHRTP53CA12CA1
Bromide SCHEMBL8758652 0.97 KDM4E (0.65) KDM4ETSHRTP53CA12CA1
Potassium SCHEMBL9719670 0.97 KDM4E (0.65) KDM4ETSHRTP53CA12CA1
SCHEMBL6666460 0.97 KDM4E (0.65) KDM4ETSHRTP53CA12CA1
SCHEMBL20942846 0.97 KDM4E (0.65) KDM4ETSHRTP53CA12CA1
Terephthalic Acid SCHEMBL2846917 0.97 TSHR (0.67) KDM4ETSHRTP53CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 65203 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6392091-B1 None US claimed
EP-4357389-B1 POLYESTER RESIN COMPRISING REGENERATED BIS(2-HYDROXYETHYL)TEREPHTHALATE AND FILM SK CHEMICALS CO LTD (KR) 2026-05-27 EP claimed
US-12637539-B2 Polyester resin composition, aqueous dispersion, coating composition, and coating film TOYOBO MC CORPORATION (JP) 2026-05-26 US claimed
US-20260138879-A1 MODIFIED LAYERED DOUBLE HYDROXIDE (LDH), PARTICLES COMPRISING SAID LDH, AND METHOD FOR PRODUCING SAID LDH KISUMA CHEMICALS B V (NL) 2026-05-21 US claimed
WO-2026104841-A1 ESTER COMPOUNDS INNOSPEC LIMITED (GB) 2026-05-21 WO claimed
WO-2026104848-A2 USES AND COMPOSITIONS INNOSPEC LIMITED (GB) 2026-05-21 WO claimed
WO-2026104829-A2 USES AND COMPOSITIONS INNOSPEC LIMITED (GB) 2026-05-21 WO claimed
EP-4743521-A1 FAST-CURED INTUMESCENT COATINGS PPG Industries Ohio, Inc. (US) 2026-05-20 EP claimed
US-12631816-B2 Light-guide sunroof assembly ENFLEX CORPORATION (TW) 2026-05-19 US claimed
US-20260132246-A1 POLYESTER RESIN COMPRISING RECYCLED MONOMERS AND POWDER COATING COMPOSITION COMPRISING THE SAME SK CHEMICALS CO LTD (KR) 2026-05-14 US claimed
US-3971752-A GLASS FIBER, ANTIMONY OXIDE, AND DECARBROMODIPHENYL ETHER OR DECBROMOPHENYL TORAY INDUSTRIES, INC. (JA) 1976-07-27 US claimed
US-3965160-A OXIDATION SUN VENTURES, INC. (US) 1976-06-22 US claimed
US-3962368-A Linear polyester molding composition containing cross-linked linear polyester as a nucleating agent HOECHST AKTIENGESELLSCHAFT (DT) 1976-06-08 US claimed
US-3956228-A Polyester resin composition for powder coatings prepared from endomethylenetetrahydrophthalic acid ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1976-05-11 US claimed
US-3951915-A Thermo-oxidative stable copolyesters THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-04-20 US claimed
US-3951905-A ANTIMONY CONTAINING PARTICLES TORAY INDUSTRIES, INC. (JA) 1976-04-20 US claimed
US-3944598-A Production of amine salts of carboxylic acids THE LUMMUS COMPANY (US) 1976-03-16 US claimed
US-3937754-A BIAXIALLY ORIENTED POLYETHYLENE-2,6-NAPHTHALATE FILM CONTAINING ANOTHER POLYESTER RESIN AND PROCESS FOR ITS PRODUCTION TEIJIN LTD (JA) 1976-02-10 US claimed
US-3936509-A Process for separating dimethyl naphthalenes comprising 2,6-dimethyl naphthalenes as main component TEIJIN LIMITED (JA) 1976-02-03 US claimed
US-3935238-A CATALYTIC ESTERIFICATION OF AMMONIUM CARBOXYLATE AND ALKANOL SUN RESEARCH AND DEVELOPMENT CO. (US) 1976-01-27 US claimed