SCHEMBL1875865

SCHEMBL1875865

C=CCCCc1ccccc1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.50
TLR8 Q9NR97 1/20 0.45
CHRM2 P08172 1/20 0.39
GPR84 Q9NQS5 1/20 0.38
ALDH1A1 P00352 3/20 0.37
USP2 O75604 1/20 0.37
HPGD P15428 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
DAO P14920 2/20 0.37
GAA P10253 1/20 0.37
KMT2A Q03164 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
CA14 Q9ULX7 1/20 0.37
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29779783 1.00 TAAR1 (0.50) TAAR1TLR8CHRM2GPR84ALDH1A1
SCHEMBL8073131 0.94 TAAR1 (0.48) TAAR1TLR8CHRM2GPR84ALDH1A1
SCHEMBL9241987 0.92 TAAR1 (0.47) TAAR1TLR8CHRM2GPR84ALDH1A1
SCHEMBL8070767 0.92 TAAR1 (0.47) TAAR1TLR8CHRM2GPR84ALDH1A1
SCHEMBL8077854 0.92 TAAR1 (0.47) TAAR1TLR8CHRM2GPR84ALDH1A1
SCHEMBL8078262 0.92 TAAR1 (0.47) TAAR1TLR8CHRM2GPR84ALDH1A1
SCHEMBL9244061 0.88 HDAC1 (0.43) TAAR1TLR8ALDH1A1USP2HPGD
SCHEMBL1240981 0.88 TAAR1 (0.54) TAAR1CHRM2GPR84ALDH1A1DAO
SCHEMBL2098064 0.86 TAAR1 (0.52) TAAR1CHRM2GPR84ALDH1A1DAO
SCHEMBL10430495 0.86 TAAR1 (0.52) TAAR1CHRM2GPR84ALDH1A1DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102300550-A Perfume systems 2011-12-28 CN claimed
US-7935856-B2 Preparation method of 1,5-dimethyltetralin using dealuminated zeolite beta catalyst HYOSUNG CORPORATION (KR) 2011-05-03 US claimed
CN-100584810-C Preparation method of 1,5-dimethyltetralin using dealuminated zeolite beta catalyst HYOSUNG CORP 2010-01-27 CN claimed
EP-1849758-B1 Preparation method of 1,5-dimethyltetralin using dealuminated zeolite beta catalyst HYOSUNG CORP (KR) 2009-03-25 EP claimed
EP-1849758-A1 Preparation method of 1,5-dimethyltetralin using dealuminated zeolite beta catalyst Hyosung Corporation (KR) 2007-10-31 EP claimed
CN-101050161-A Preparation method of 1,5-dimethyltetralin using dealuminated zeolite beta catalyst HYOSUNG CORP (KR) 2007-10-10 CN claimed
US-20070232842-A1 Preparation method of 1,5-dimethyltetralin using dealuminated zeolite beta catalyst HYOSUNG CORPORATION (KR) 2007-10-04 US claimed
WO-2004058666-A1 PREPARATION METHOD OF 1,5-DIMETHYLTETRALIN HYOSUNG CORPORATION (KR) 2004-07-15 WO claimed
EP-0926114-B1 Crystallization of 2,6-Dimethylnaphthalene BP CORP NORTH AMERICA INC (US) 2004-05-19 EP claimed
EP-1368297-A2 SYNTHESIS AND USE OF DIMETHYL-1,5-NAPHTHALENEDICARBOXYLATES AND INTERMEDIATES THEREFROM BP Corporation North America Inc. (US) 2003-12-10 EP claimed
EP-0687248-A4 CRYSTALLIZATION OF 2,6-DIMETHYLNAPHTHALENE AMOCO CORP (US) 1996-05-01 EP claimed
US-5510563-A ALKENYLATION, CYCLIZATION, DEHYDROGENATION, AND ISOMERIZATION AMOCO CORPORATION (US) 1996-04-23 US claimed
EP-0687248-A1 CRYSTALLIZATION OF 2,6-DIMETHYLNAPHTHALENE AMOCO CORPORATION (US) 1995-12-20 EP claimed
WO-1995018086-A1 CRYSTALLIZATION OF 2,6-DIMETHYLNAPHTHALENE AMOCO CORPORATION (US) 1995-07-06 WO claimed
EP-0461913-B1 Catalytic alkenylbenzene cyclization AMOCO CORP (US) 1995-02-22 EP claimed
US-5365001-A Catalytic cyclization of alkenebenzene in the presence of hydrogen TEIJIN LIMITED (JP) 1994-11-15 US claimed
EP-0594856-A1 PROCESS FOR PRODUCING DIALKYLNAPHTHALENE TEIJIN LIMITED (JP) 1994-05-04 EP claimed
EP-0461913-A2 Catalytic alkenylbenzene cyclization AMOCO CORPORATION (US) 1991-12-18 EP claimed
US-5034561-A Formation of dialkyltetrahydronaphthalene in the presence of a zeolite catalyst AMOCO CORPORATION (US) 1991-07-23 US claimed
US-4740647-A COPPER ALUMINUM BORATE TO CATALYZE DEHYDROCYCLIZATION OF ALKENYL AROMATIC COMPOUND AMOCO CORPORATION (US) 1988-04-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070232842-A1 Preparation method of 1,5-dimethyltetralin using dealuminated zeolite beta catalyst DERA, DIMT1, MGST1 TAAR1 893/4885TLR8 4023/4885CHRM2 2874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.