Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | NMT1 | P30419 | 11/20 | 0.39 |
| ▸ | NMT2 | O60551 | 10/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18786235 | 0.99 | EPHX1 (0.40) | EPHX1NMT1NMT2EPHX2GRIN1 | |
| SCHEMBL18760191 | 0.96 | NMT1 (0.44) | EPHX1NMT1NMT2GRIN1GRIN2A | |
| SCHEMBL23840117 | 0.93 | NMT1 (0.40) | EPHX1NMT1NMT2 | |
| SCHEMBL22223575 | 0.93 | EPHX1 (0.41) | EPHX1NMT1NMT2EPHX2HDAC1 | |
| SCHEMBL18785521 | 0.86 | NMT1 (0.37) | NMT1NMT2MMP1MMP3 | |
| SCHEMBL20634648 | 0.85 | NMT1 (0.42) | NMT1NMT2EPHX2 | |
| SCHEMBL23840130 | 0.85 | NMT1 (0.42) | NMT1NMT2EPHX2 | |
| SCHEMBL20633489 | 0.83 | NMT1 (0.41) | NMT1NMT2 | |
| SCHEMBL23840017 | 0.83 | NMT1 (0.46) | NMT1NMT2 | |
| SCHEMBL18760192 | 0.83 | NMT1 (0.46) | NMT1NMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066349-A1 | VE-CADHERIN BINDING BIOCONJUGATE | SYMIC IP, LLC (US) | 2017-04-20 | — | — | WO | disclosed |