Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 20/20 | 0.68 |
| ▸ | PDCD1 | Q15116 | 16/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29615271 | 0.97 | CD274 (0.71) | CD274PDCD1 | |
| SCHEMBL31137979 | 0.97 | CD274 (0.71) | CD274PDCD1 | |
| SCHEMBL19897879 | 0.97 | CD274 (0.71) | CD274PDCD1 | |
| SCHEMBL21792202 | 0.95 | CD274 (0.64) | CD274PDCD1 | |
| SCHEMBL21623439 | 0.95 | CD274 (0.68) | CD274PDCD1 | |
| SCHEMBL21792210 | 0.94 | CD274 (0.63) | CD274PDCD1 | |
| SCHEMBL20539577 | 0.94 | CD274 (0.67) | CD274PDCD1 | |
| SCHEMBL29724547 | 0.94 | CD274 (0.67) | CD274PDCD1 | |
| SCHEMBL20540260 | 0.93 | CD274 (0.66) | CD274PDCD1 | |
| SCHEMBL20539235 | 0.93 | CD274 (0.68) | CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066227-A1 | COMPOUNDS USEFUL AS IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-04-20 | — | — | WO | disclosed |