Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 8/20 | 0.57 |
| ▸ | CACNA1B | Q00975 | 7/20 | 0.57 |
| ▸ | CACNA1C | Q13936 | 6/20 | 0.57 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | TACR1 | P25103 | 3/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.32 |
| ▸ | POLQ | O75417 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15844410 | 0.78 | CACNA1H (0.73) | CACNA1HCACNA1BCACNA1CCACNA1GALDH1A1 | |
| SCHEMBL17437477 | 0.73 | CACNA1H (1.00) | CACNA1HCACNA1BCACNA1CCACNA1G | |
| SCHEMBL20088386 | 0.67 | CACNA1H (0.61) | CACNA1HCACNA1BCACNA1CCACNA1G | |
| SCHEMBL15844326 | 0.67 | CACNA1H (0.72) | CACNA1HCACNA1BCACNA1CCACNA1GALDH1A1 | |
| SCHEMBL15844216 | 0.62 | CACNA1H (0.71) | CACNA1HCACNA1BCACNA1CCACNA1G | |
| SCHEMBL19868013 | 0.61 | CSNK1D (0.64) | — | |
| SCHEMBL19868016 | 0.60 | CSNK1D (0.53) | CACNA1HCACNA1BCACNA1CCACNA1G | |
| SCHEMBL15844641 | 0.59 | CACNA1H (0.53) | CACNA1HCACNA1BCACNA1CCACNA1GALDH1A1 | |
| SCHEMBL15844285 | 0.59 | CACNA1H (0.53) | CACNA1HCACNA1BCACNA1CCACNA1GALDH1A1 | |
| SCHEMBL15844307 | 0.59 | CACNA1H (0.52) | CACNA1HCACNA1BCACNA1CCACNA1GALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170107203-A1 | HETEROCYCLIC INHIBITORS OF THE SODIUM CHANNEL | EPIRUS BIOPHARMACEUTICALS, INC. (US) | 2017-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170107203-A1 | HETEROCYCLIC INHIBITORS OF THE SODIUM CHANNEL | SCN1B, SCN1A, CACNA1S | CACNA1H 20/4885CACNA1B 5/4885CACNA1C 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.