Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18768625 | 0.96 | KDM4E (0.52) | KDM4EMAPTBCHEMAOAACHE | |
| SCHEMBL18768367 | 0.88 | BCHE (0.50) | BCHE | |
| SCHEMBL18768427 | 0.87 | — | — | |
| SCHEMBL18767294 | 0.86 | BCHE (0.49) | BCHEMAOAACHEMAOB | |
| SCHEMBL18768447 | 0.85 | BCHE (0.52) | KDM4EBCHEMAOAACHEMAOB | |
| SCHEMBL18768548 | 0.81 | KDM4E (0.52) | KDM4EMAPTMEN1KMT2A | |
| SCHEMBL18768428 | 0.81 | BCHE (0.49) | KDM4EBCHEMAOAACHEMAOB | |
| SCHEMBL18768581 | 0.80 | BCHE (0.52) | KDM4EBCHEMAOAACHEMAOB | |
| SCHEMBL18768434 | 0.80 | — | — | |
| SCHEMBL18768590 | 0.79 | MEN1 (0.52) | KDM4EBCHEMAOAACHEMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066705-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE AGAINST STRESS GRANULES | AQUINNAH PHARMACEUTICALS, INC. (US) | 2017-04-20 | — | — | WO | disclosed |