Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 6/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18767977 | 0.90 | BCHE (0.44) | AKR1C3FLT3HRH4TRPM8BCHE | |
| SCHEMBL18767441 | 0.89 | AKR1C3 (0.43) | AKR1C3 | |
| SCHEMBL18768593 | 0.89 | AKR1C3 (0.44) | AKR1C3FLT3HRH4BCHE | |
| SCHEMBL18768177 | 0.86 | FLT3 (0.44) | AKR1C3FLT3 | |
| SCHEMBL18768455 | 0.83 | BCHE (0.42) | AKR1C3FLT3HRH4BCHE | |
| SCHEMBL18768598 | 0.81 | AKR1C3 (0.46) | AKR1C3FLT3 | |
| SCHEMBL18768433 | 0.80 | HRH4 (0.57) | AKR1C3HRH4 | |
| SCHEMBL18767864 | 0.80 | AKR1C3 (0.48) | AKR1C3 | |
| SCHEMBL18768585 | 0.80 | AKR1C3 (0.50) | AKR1C3HRH4 | |
| SCHEMBL18768402 | 0.78 | AKR1C3 (0.52) | AKR1C3HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066705-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE AGAINST STRESS GRANULES | AQUINNAH PHARMACEUTICALS, INC. (US) | 2017-04-20 | — | — | WO | disclosed |