Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | LAP3 | P28838 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 4/20 | 0.39 |
| ▸ | MMP2 | P08253 | 4/20 | 0.39 |
| ▸ | MMP8 | P22894 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 3/20 | 0.38 |
| ▸ | FDPS | P14324 | 3/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18769274 | 0.89 | SMPD1 (0.47) | SMPD1PTPN1LAP3MMP1MMP2 | |
| SCHEMBL1921579 | 0.87 | SMPD1 (0.41) | SMPD1PTPN1LAP3MMP1MMP2 | |
| SCHEMBL18759027 | 0.87 | SMPD1 (0.37) | SMPD1PTPN1LAP3MMP1MMP2 | |
| SCHEMBL18759030 | 0.87 | SMPD1 (0.37) | SMPD1PTPN1LAP3MMP1MMP2 | |
| SCHEMBL5963398 | 0.85 | SMPD1 (0.39) | SMPD1PTPN1LAP3MMP1MMP2 | |
| SCHEMBL9648815 | 0.85 | PTPN1 (0.46) | SMPD1PTPN1LAP3MMP1MMP2 | |
| SCHEMBL29059648 | 0.84 | SMPD1 (0.38) | SMPD1PTPN1LAP3MMP1MMP2 | |
| SCHEMBL28488486 | 0.84 | SMPD1 (0.38) | SMPD1PTPN1LAP3 | |
| SCHEMBL11026179 | 0.84 | SMPD1 (0.38) | SMPD1PTPN1LAP3 | |
| SCHEMBL6470157 | 0.82 | PTPN1 (0.47) | SMPD1PTPN1LAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066793-A1 | MRNA CAP ANALOGS AND METHODS OF MRNA CAPPING | MODERNATX, INC. (US) | 2017-04-20 | — | — | WO | disclosed |
| WO-2017066781-A1 | MRNA CAP ANALOGS WITH MODIFIED PHOSPHATE LINKAGE | MODERNATX, INC. (US) | 2017-04-20 | — | — | WO | disclosed |