Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 20/20 | 1.00 |
| ▸ | PDE2A | O00408 | 3/20 | 0.93 |
| ▸ | PDE8A | O60658 | 3/20 | 0.93 |
| ▸ | PDE5A | O76074 | 3/20 | 0.93 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.93 |
| ▸ | PDE11A | Q9HCR9 | 3/20 | 0.93 |
| ▸ | PDE7B | Q9NP56 | 3/20 | 0.93 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.93 |
| ▸ | PDE9A | O76083 | 2/20 | 0.93 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.93 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.93 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.93 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.93 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lenrispodun SCHEMBL18211963 | 1.00 | PDE4A (1.00) | PDE4APDE2APDE8APDE5APDE3B | |
| Lenrispodun SCHEMBL29415040 | 1.00 | PDE4A (1.00) | PDE4APDE2APDE8APDE5APDE3B | |
| Lenrispodun SCHEMBL10201342 | 1.00 | PDE4A (1.00) | PDE4APDE2APDE8APDE5APDE3B | |
| Lenrispodun SCHEMBL16324627 | 1.00 | PDE4A (1.00) | PDE4APDE2APDE8APDE5APDE3B | |
| SCHEMBL20341393 | 0.98 | PDE4A (0.97) | PDE4APDE2APDE8APDE5APDE3B | |
| Lenrispodun SCHEMBL23610593 | 0.96 | PDE4A (1.00) | PDE4APDE2APDE8APDE5APDE3B | |
| Lenrispodun SCHEMBL21225678 | 0.96 | PDE4A (1.00) | PDE4APDE2APDE8APDE5APDE3B | |
| Lenrispodun SCHEMBL30357428 | 0.96 | PDE4A (1.00) | PDE4APDE2APDE8APDE5APDE3B | |
| Lenrispodun SCHEMBL17766669 | 0.96 | PDE4A (0.92) | PDE4APDE2APDE8APDE5APDE3B | |
| SCHEMBL8060473 | 0.94 | PDE4A (0.88) | PDE4APDE2APDE8APDE5APDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4395767-A2 | CO-CRYSTALS | Intra-Cellular Therapies, Inc. (US) | 2024-07-10 | — | — | EP | claimed |
| WO-2023034965-A2 | CO-CRYSTALS | INTRA-CELLULAR THERAPIES, INC. (US) | 2023-03-09 | — | — | WO | claimed |
| EP-4469052-A1 | NOVEL COMPOSITIONS | Intra-Cellular Therapies, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023147484-A1 | NOVEL COMPOSITIONS | INTRA-CELLULAR THERAPIES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| US-9849132-B2 | Products and pharmaceutical compositions | INTRA-CELLULAR THERAPIES, INC. (US) | 2017-12-26 | — | — | US | disclosed |
| US-9630971-B2 | Free base crystals | INTRA-CELLULAR THERAPIES, INC. (US) | 2017-04-25 | — | — | US | disclosed |