Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 20/20 | 0.62 |
| ▸ | TLR7 | Q9NYK1 | 11/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18772009 | 0.89 | TLR8 (0.78) | TLR8TLR7 | |
| SCHEMBL18772027 | 0.89 | TLR8 (0.77) | TLR8TLR7 | |
| SCHEMBL1800351 | 0.88 | TLR8 (0.79) | TLR8TLR7 | |
| SCHEMBL18772004 | 0.88 | TLR8 (0.69) | TLR8TLR7 | |
| SCHEMBL18772034 | 0.88 | TLR8 (0.69) | TLR8TLR7 | |
| SCHEMBL18772061 | 0.87 | TLR8 (0.55) | TLR8TLR7 | |
| SCHEMBL18771724 | 0.86 | TLR8 (0.56) | TLR8TLR7 | |
| SCHEMBL18772102 | 0.85 | TLR8 (0.67) | TLR8TLR7 | |
| SCHEMBL18772181 | 0.85 | TLR8 (0.71) | TLR8TLR7 | |
| SCHEMBL18772057 | 0.85 | TLR8 (0.71) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3159337-A2 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | Ventirx Pharmaceuticals, Inc. (US) | 2017-04-26 | — | — | EP | disclosed |