SCHEMBL18774697

SCHEMBL18774697

CCO[Si](C)(C)CCc1ccc(N)cc1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GFER P55789 1/20 0.46
MAOB P27338 4/20 0.41
MAOA P21397 2/20 0.41
CYP19A1 P11511 5/20 0.41
TSHR P16473 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
MAPT P10636 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
ALDH1A1 P00352 1/20 0.37
CYP3A4 P08684 1/20 0.37
TAAR1 Q96RJ0 1/20 0.36
PPIB P23284 1/20 0.36
PPIA P62937 1/20 0.36
PPID Q08752 1/20 0.36
PPIG Q13427 1/20 0.36
LOXL2 Q9Y4K0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4812061 0.90 CYP4F2 (0.36) TAAR1
SCHEMBL7119771 0.85 GFER (0.46) GFERMAOBMAOACYP19A1TSHR
SCHEMBL12458734 0.83 CYP4F2 (0.33)
SCHEMBL14156561 0.83 CYP4F2 (0.33) TAAR1
SCHEMBL8960954 0.83 GFER (0.48) GFERMAOBMAOACYP19A1TSHR
SCHEMBL12458723 0.83 CYP4F2 (0.33)
SCHEMBL26185016 0.82 GFER (0.52) GFERMAOBMAOACYP19A1TSHR
SCHEMBL29279782 0.81 CYP3A4 (0.35) CYP3A4
SCHEMBL15733742 0.81 TAAR1 (0.41) MAOBTAAR1
SCHEMBL927506 0.81 CYP4F2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170114249-A1 HEXAHYDROTRIAZINE HYBRID COATINGS FOR SULFUR CAPTURE INTERNATIONAL BUSINESS MACHINES CORPORATION 2017-04-27 US disclosed