⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22732394 | 1.00 | — | — | |
| SCHEMBL18872279 | 1.00 | — | — | |
| SCHEMBL230088 | 0.82 | — | — | |
| SCHEMBL1874509 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL6631187 | 0.80 | — | — | |
| Iodide SCHEMBL10533464 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL28103594 | 0.80 | — | — | |
| Water SCHEMBL3390484 | 0.80 | — | — | |
| Bromide SCHEMBL28103590 | 0.80 | — | — | |
| SCHEMBL24000122 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152237-A1 | BIS-PYRINDINO CONTAINING COMPOUNDS FOR THE USE IN THE TREATMENT OF CNS PATHOLOGIES | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2010-06-17 | — | — | US | claimed |
| US-20080287490-A1 | Bis-pyridino containing compounds for the use in the treatment of CNS pathologies | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2008-11-20 | — | — | US | claimed |
| US-20050261334-A1 | Bis-pyridino containing compounds for the use in the treatment of CNS pathologies | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2005-11-24 | — | — | US | claimed |
| US-12624164-B2 | Synthetic thickeners incorporating non-reactive diluents | HERCULES LLC (US) | 2026-05-12 | — | — | US | disclosed |
| WO-2023133229-A2 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-07-13 | — | — | WO | disclosed |
| WO-2023133217-A1 | 2-(INDAZOL-5-YL)-6-(PIPERIDIN-4-YL)-1,7-NAPHTHYRIDINE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS FOR SPLICING NUCLEIC ACIDS AND FOR THE TREATMENT OF PROLIFERATIVE DISEASES | REMIX THERAPEUTICS INC. (US) | 2023-07-13 | — | — | WO | disclosed |
| WO-2023034836-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-03-09 | — | — | WO | disclosed |
| WO-2023034812-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-03-09 | — | — | WO | disclosed |
| US-20220289908-A1 | SYNTHETIC THICKENERS INCORPORATING NON-REACTIVE DILUENTS | HERCULES LLC (US) | 2022-09-15 | — | — | US | disclosed |
| EP-4007787-A1 | SYNTHETIC THICKENERS INCORPORATING NON-REACTIVE DILUENTS | Hercules LLC (US) | 2022-06-08 | — | — | EP | disclosed |
| WO-2022006543-A1 | 5-[5-(PIPERIDIN-4-YL)THIENO[3,2-C]PYRAZOL-2-YL]INDAZOLE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS FOR SPLICING NUCLEIC ACIDS AND FOR THE TREATMENT OF PROLIFERATIVE DISEASES | REMIX THERAPEUTICS INC. (US) | 2022-01-06 | — | — | WO | disclosed |
| US-20080287490-A1 | Bis-pyridino containing compounds for the use in the treatment of CNS pathologies | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2008-11-20 | — | — | US | disclosed |
| US-7375110-B2 | N-aryl diazaspiracyclic compounds and methods of preparation and use thereof | TARGACEPT, INC. (US) | 2008-05-20 | — | — | US | disclosed |
| US-20050261334-A1 | Bis-pyridino containing compounds for the use in the treatment of CNS pathologies | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2005-11-24 | — | — | US | disclosed |
| EP-0504448-B1 | Process for the preparation of polyurea elastomerbased foamed masses | HUNTSMAN INTERNATIONAL TRADING (DE) | 2000-01-12 | — | — | EP | disclosed |
| US-5270014-A | Apparatus for producing a foamed mass of a polyurea elastomer | KRAUSS-MAFFEI AG (DE) | 1993-12-14 | — | — | US | disclosed |
| US-5189073-A | From polyetheramine and polyisocyanate; using tertiary amine catalyst and halogen-free blowing agent | TEXACO CHEMICAL CO. (US) | 1993-02-23 | — | — | US | disclosed |
| US-5157059-A | Feeding polyetheramine, polyisocyanate, and water into mold to form low density foams | KRAUSS-MAFFEI AG (DE) | 1992-10-20 | — | — | US | disclosed |
| EP-0504447-A1 | Process and device for the preparation of foamed masses based on polyurea-elastomers | Krauss-Maffei Aktiengesellschaft (DE) | 1992-09-23 | — | — | EP | disclosed |
| EP-0504448-A1 | Process for the preparation of polyurea elastomerbased foamed masses | Huntsman International Trading Deutschland GmbH (DE) | 1992-09-23 | — | — | EP | disclosed |