⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18193387 | 0.95 | — | — | |
| SCHEMBL18193388 | 0.92 | — | — | |
| SCHEMBL15257356 | 0.91 | — | — | |
| SCHEMBL15257372 | 0.89 | — | — | |
| SCHEMBL15257378 | 0.86 | CSNK1D (0.30) | — | |
| SCHEMBL18776492 | 0.85 | — | — | |
| SCHEMBL15259033 | 0.84 | — | — | |
| SCHEMBL15257346 | 0.84 | — | — | |
| SCHEMBL15257340 | 0.83 | — | — | |
| SCHEMBL18193389 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170114086-A1 | 2'- SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. | 2017-04-27 | — | — | US | disclosed |
| US-9481704-B2 | 2′-substituted carba-nucleoside analogs for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2016-11-01 | — | — | US | disclosed |