Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 7/20 | 0.64 |
| ▸ | EDNRA | P25101 | 1/20 | 0.62 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.56 |
| ▸ | IL1RN | P18510 | 6/20 | 0.54 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.54 |
| ▸ | ECE1 | P42892 | 5/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | CASP4 | P49662 | 1/20 | 0.52 |
| ▸ | CASP5 | P51878 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | CASP9 | P55211 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.52 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1877672 | 1.00 | ERAP2 (0.64) | ERAP2EDNRAMAGI3IL1RNERAP1 | |
| SCHEMBL29595782 | 0.94 | EDNRA (0.66) | ERAP2EDNRAMAGI3IL1RNERAP1 | |
| SCHEMBL30050836 | 0.93 | EDNRA (0.63) | ERAP2EDNRAMAGI3IL1RNERAP1 | |
| SCHEMBL30093051 | 0.93 | EDNRA (0.63) | ERAP2EDNRAMAGI3IL1RNERAP1 | |
| SCHEMBL30839328 | 0.93 | ERAP2 (0.73) | ERAP2IL1RNERAP1ECE1KMT2A | |
| SCHEMBL30093046 | 0.91 | EDNRA (0.69) | ERAP2EDNRAIL1RNERAP1ECE1 | |
| SCHEMBL30533184 | 0.90 | EDNRA (0.76) | ERAP2EDNRAIL1RNERAP1ECE1 | |
| SCHEMBL30680479 | 0.89 | ERAP2 (0.62) | ERAP2EDNRAMAGI3IL1RNERAP1 | |
| SCHEMBL29354013 | 0.89 | ERAP2 (0.76) | ERAP2IL1RNERAP1ECE1ACE | |
| SCHEMBL30660136 | 0.89 | EDNRA (0.58) | ERAP2EDNRAMAGI3IL1RNERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9366671-B2 | Immunogenic proteins of Leptospira | CORNELL RESEARCH FOUNDATION, INC. (US) | 2016-06-14 | — | — | US | disclosed |
| US-20160103128-A1 | NOVEL IMMUNOGENIC PROTEINS OF LEPTOSPIRA | UNIV CORNELL (US) | 2016-04-14 | — | — | US | disclosed |
| EP-2447278-B1 | Novel immunogenic proteins of Leptospira | CORNELL RES FOUNDATION INC (US) | 2015-04-08 | — | — | EP | disclosed |
| US-8900825-B2 | Immunogenic proteins of Leptospira | CORNELL RESEARCH FOUNDATION, INC. (US) | 2014-12-02 | — | — | US | disclosed |
| US-20140186860-A1 | NOVEL IMMUNOGENIC PROTEINS OF LEPTOSPIRA | CORNELL UNIVERSITY (US) | 2014-07-03 | — | — | US | disclosed |
| EP-1565080-B1 | NOVEL IMMUNOGENIC PROTEINS OF LEPTOSPIRA | CORNELL RES FOUNDATION INC (US) | 2014-01-15 | — | — | EP | disclosed |
| EP-2447278-A1 | Novel immunogenic proteins of Leptospira | Cornell Research Foundation, Inc. (US) | 2012-05-02 | — | — | EP | disclosed |
| US-8168207-B2 | Immunogenic proteins of leptospira | CORNELL RESEARCH FOUNDATION, INC. (US) | 2012-05-01 | — | — | US | disclosed |
| US-20110110966-A1 | NOVEL IMMUNOGENIC PROTEINS OF LEPTOSPIRA | CORNELL UNIVERSITY (US) | 2011-05-12 | — | — | US | disclosed |
| US-7655427-B2 | Using immunogenic proteins LigA and LigB from Leptospira in development of effective vaccines and antibodies; detection of pathogenic Leptospira infection in a mammal | CORNELL RESEARCH FOUNDATION, INC. (US) | 2010-02-02 | — | — | US | disclosed |
| US-20050271680-A1 | Using immunogenic proteins LigA and LigB from Leptospira in development of effective vaccines and antibodies; detection of pathogenic Leptospira infection in a mammal | CORNELL RESEARCH FOUNDATION, INC. | 2005-12-08 | — | — | US | disclosed |