Sugi Predict

Sugi Predict / Compounds / SCHEMBL18777935

SCHEMBL18777935

SCHEMBL18777935

c1cc(-c2ccc(-c3cccc(-c4cnc5c6ccccc6c6ccccc6c5n4)c3)cc2)cc(-c2cccc(-n3c4ccccc4c4ccccc43)c2)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.37
▸ ATM Q13315 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ ASIC3 Q9UHC3 1/20 0.33
▸ PDE10A Q9Y233 1/20 0.32
▸ NPC1 O15118 2/20 0.32
▸ RAB9A P51151 2/20 0.32
▸ DHFR P00374 1/20 0.32
▸ MAPT P10636 2/20 0.31
▸ PDGFRB P09619 1/20 0.31
▸ KDR P35968 1/20 0.31
▸ FLT3 P36888 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ PIK3CG P48736 2/20 0.30
▸ PIK3CA P42336 1/20 0.30
▸ PIK3CB P42338 1/20 0.30
▸ HDAC6 Q9UBN7 1/20 0.30
▸ GRM5 P41594 1/20 0.30
▸ MEN1 O00255 1/20 0.30
▸ GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18777844 1.00 KDM4E (0.37) KDM4EATML3MBTL1ASIC3PDE10A
SCHEMBL18777986 1.00 KDM4E (0.37) KDM4EATML3MBTL1ASIC3PDE10A
SCHEMBL18777933 1.00 KDM4E (0.37) KDM4EATML3MBTL1ASIC3PDE10A
SCHEMBL18777848 0.98 KDM4E (0.37) KDM4EATML3MBTL1ASIC3PDE10A
SCHEMBL18777990 0.98 KDM4E (0.37) KDM4EATML3MBTL1ASIC3PDE10A
SCHEMBL18777980 0.98 KDM4E (0.37) KDM4EATML3MBTL1ASIC3PDE10A
SCHEMBL18777888 0.98 KDM4E (0.37) KDM4EATML3MBTL1ASIC3PDE10A
SCHEMBL18777936 0.97 KDM4E (0.39) KDM4EATML3MBTL1ASIC3PDE10A
SCHEMBL2403382 0.97 KDM4E (0.39) KDM4EATML3MBTL1ASIC3PDE10A
SCHEMBL29362965 0.97 KDM4E (0.39) KDM4EATML3MBTL1ASIC3PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11522138-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2022-12-06 — — US disclosed
US-20170117487-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-04-27 — — US disclosed
US-20170117487-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-04-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170117487-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device RECQL, HSF1, DDX41 KDM4E 2319/4885ATM 1948/4885L3MBTL1 1123/4885
US-11522138-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device RECQL, HSF1, DDX41 KDM4E 2319/4885ATM 1948/4885L3MBTL1 1123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.