Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.82 |
| ▸ | JAK3 | P52333 | 1/20 | 0.56 |
| ▸ | BTK | Q06187 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18778428 | 0.93 | EGFR (0.71) | EGFRJAK3BTK | |
| SCHEMBL17197357 | 0.90 | EGFR (1.00) | EGFRJAK3BTK | |
| SCHEMBL18778502 | 0.90 | EGFR (0.81) | EGFRJAK3BTK | |
| SCHEMBL18778474 | 0.88 | EGFR (0.82) | EGFRJAK3BTK | |
| SCHEMBL18778501 | 0.87 | EGFR (0.82) | EGFRJAK3BTK | |
| SCHEMBL18778500 | 0.86 | EGFR (0.72) | EGFRJAK3 | |
| SCHEMBL18778498 | 0.86 | EGFR (0.83) | EGFRJAK3 | |
| SCHEMBL18778477 | 0.85 | EGFR (0.61) | EGFRJAK3BTK | |
| SCHEMBL18778495 | 0.85 | EGFR (0.69) | EGFRJAK3BTK | |
| SCHEMBL18778499 | 0.85 | EGFR (0.84) | EGFRJAK3BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170112833-A1 | Tyrosine Kinase Inhibitor And Uses Thereof | Xuanzhu Pharma Co., Ltd. (CN) | 2017-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170112833-A1 | Tyrosine Kinase Inhibitor And Uses Thereof | EGFR, ERBB2, ABL1 | EGFR 1/4885JAK3 24/4885BTK 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.