Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.59 |
| ▸ | ALK | Q9UM73 | 19/20 | 0.58 |
| ▸ | INSR | P06213 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18779940 | 0.88 | MAP4K1 (0.73) | MAP4K1ALK | |
| SCHEMBL18779878 | 0.87 | ALK (0.77) | ALK | |
| SCHEMBL18779889 | 0.81 | MAP4K1 (0.54) | MAP4K1ALK | |
| SCHEMBL18875066 | 0.80 | ALK (0.69) | ALKINSR | |
| SCHEMBL18779885 | 0.77 | ALK (0.61) | MAP4K1ALKINSR | |
| SCHEMBL18779986 | 0.77 | ALK (0.63) | MAP4K1ALKINSR | |
| SCHEMBL18760005 | 0.75 | ALK (0.76) | MAP4K1ALKINSR | |
| SCHEMBL20214385 | 0.75 | MAP4K1 (1.00) | MAP4K1ALKINSR | |
| SCHEMBL18779884 | 0.74 | ALK (0.70) | MAP4K1ALKINSR | |
| SCHEMBL18759895 | 0.74 | ALK (0.66) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3159338-A2 | PYRIMIDINE-2,4-DIAMINE DERIVATIVE AND ANTICANCER PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE INGREDIENT | Korea Research Institute of Chemical Technology (KR) | 2017-04-26 | — | — | EP | disclosed |