SCHEMBL18780397

SCHEMBL18780397

C[C@@H](C=O)C[C@H](N)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.60
SLC1A3 P43003 6/20 0.54
SLC1A2 P43004 6/20 0.54
SLC1A1 P43005 6/20 0.54
GRIK1 P39086 13/20 0.47
GRIK2 Q13002 11/20 0.47
GRIA2 P42262 2/20 0.47
GRIA4 P48058 2/20 0.47
GRIK3 Q13003 2/20 0.47
GRIK5 Q16478 2/20 0.47
GRIA1 P42261 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20262105 1.00 SLC7A5 (0.60) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1
SCHEMBL30887303 1.00 SLC7A5 (0.60) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1
SCHEMBL20262104 1.00 SLC7A5 (0.60) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1
SCHEMBL2231422 0.80 SLC7A5 (0.58) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1
SCHEMBL7460993 0.80 SLC7A5 (0.58) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1
SCHEMBL9102865 0.80 SLC7A5 (0.58) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1
SCHEMBL28259356 0.78 RNPEP (0.37) SLC7A5SLC1A3SLC1A2SLC1A1
D-Leucine SCHEMBL22413004 0.77 SLC7A5 (0.82) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1
D-Leucine SCHEMBL1234878 0.77 SLC7A5 (0.82) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1
Leucine SCHEMBL1236251 0.77 SLC7A5 (0.82) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4684030-A2 METHOD OF DEPROTECTING AT LEAST ONE D-AMINO ACID AND/OR D-AMINO ACID DERIVATIVE PROTECTED FUNCTIONAL GROUP Martin-Luther-Universität Halle-Wittenberg (DE) 2026-01-28 EP disclosed
WO-2024227957-A2 METHOD OF DEPROTECTING AT LEAST ONE D-AMINO ACID AND/OR D-AMINO ACID DERIVATIVE PROTECTED FUNCTIONAL GROUP Martin-Luther-Universität Halle-Wittenberg (DE) 2024-11-07 WO disclosed
EP-3335720-A1 C-DI-GMP BINDING PEPTIDES Universität Basel (CH) 2018-06-20 EP disclosed
US-9629911-B2 Photoreactive regulator of protein function and methods of use thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-04-25 US disclosed