SCHEMBL18783333

SCHEMBL18783333

O=[N+]([O-])c1ccccc1C1OC(c2ccccc2)OC1CNS(=O)(=O)O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.36
KMT2A Q03164 5/20 0.35
MAPT P10636 3/20 0.35
MEN1 O00255 3/20 0.35
ALDH1A1 P00352 3/20 0.35
KDM4E B2RXH2 2/20 0.35
CA2 P00918 2/20 0.35
CA1 P00915 1/20 0.35
MMP1 P03956 1/20 0.35
MMP2 P08253 1/20 0.35
MMP9 P14780 1/20 0.35
MMP8 P22894 1/20 0.35
MMP13 P45452 1/20 0.35
KDM1A O60341 1/20 0.34
DNMT3B Q9UBC3 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
ABCC4 O15439 1/20 0.33
PLIN1 O60240 1/20 0.33
CACNA1F O60840 1/20 0.33
GMNN O75496 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18783331 1.00 CA12 (0.36) CA12KMT2AMAPTMEN1ALDH1A1
SCHEMBL15551602 0.84 DNMT3B (0.38) KMT2AMAPTMEN1ALDH1A1KDM4E
SCHEMBL30444549 0.84 DNMT3B (0.38) KMT2AMAPTMEN1ALDH1A1KDM4E
SCHEMBL18186743 0.84 DNMT3B (0.38) KMT2AMAPTMEN1ALDH1A1KDM4E
SCHEMBL18802935 0.84 DNMT3B (0.38) KMT2AMAPTMEN1ALDH1A1KDM4E
SCHEMBL30444292 0.84 DNMT3B (0.38) KMT2AMAPTMEN1ALDH1A1KDM4E
SCHEMBL15550765 0.84 DNMT3B (0.38) KMT2AMAPTMEN1ALDH1A1KDM4E
SCHEMBL20566196 0.81
SCHEMBL20565688 0.81 HDAC4 (0.36) KMT2AALDH1A1LMNATSHR
SCHEMBL20565828 0.81 HDAC4 (0.36) KMT2AALDH1A1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3079685-B1 SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN BIO PHARM SOLUTIONS CO LTD (KR) 2018-11-28 EP claimed
EP-2861571-B1 PHENYLALKYL SULFAMATE COMPOUND AND MUSCLE RELAXANT COMPOSITION COMPRISING THE SAME BIO-PHARM SOLUTIONS CO LTD (KR) 2017-05-03 EP claimed