SCHEMBL18792500

SCHEMBL18792500

CN1CCN(C(=O)N2CCN(C(=O)C(C)(C)C)CC2)CC1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ALDH1A1 P00352 2/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
HTR1A P08908 1/20 0.39
RIPK1 Q13546 1/20 0.39
BCHE P06276 1/20 0.38
CHRM1 P11229 3/20 0.37
CHRM3 P20309 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
CHRM4 P08173 1/20 0.37
CHRM5 P08912 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL188325 0.93 CYP1A2 (0.54) CYP1A2TDP1MEN1KMT2AHPGD
SCHEMBL24339467 0.85 HTT (0.52) CYP1A2TDP1MEN1KMT2AHPGD
SCHEMBL10722471 0.83 MEN1 (0.52) MEN1KMT2AALDH1A1RIPK1HDAC6
SCHEMBL673083 0.83
SCHEMBL5470776 0.83 CYP1A2 (0.65) CYP1A2TDP1MEN1KMT2ANPSR1
Hydrochloric Acid SCHEMBL15209250 0.81 CYP1A2 (0.62) CYP1A2TDP1MEN1KMT2ANPSR1
SCHEMBL16886301 0.79 MEN1 (0.61) MEN1KMT2AALDH1A1
SCHEMBL12139778 0.78 CYP1A2 (0.48) CYP1A2TDP1NPSR1ALDH1A1HPGD
SCHEMBL26551072 0.77 GAA (0.48) CYP1A2TDP1MEN1KMT2AALDH1A1
SCHEMBL14013018 0.77 CYP1A2 (0.52) CYP1A2TDP1HPGDALOX15HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9629924-B2 Conjugates of CC-1065 analogs and bifunctional linkers SYNTARGA BV (NL) 2017-04-25 US disclosed