SCHEMBL1879330

SCHEMBL1879330

CCC=CCc1ccccc1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.48
MAPT P10636 2/20 0.41
KMT2A Q03164 3/20 0.40
PTGER1 P34995 1/20 0.39
PTGER4 P35408 1/20 0.39
PTGER3 P43115 1/20 0.39
PTGER2 P43116 1/20 0.39
ACHE P22303 2/20 0.38
TSHR P16473 1/20 0.38
CHRM2 P08172 1/20 0.37
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37
ALDH1A1 P00352 3/20 0.36
MAOB P27338 2/20 0.36
CYP2A13 Q16696 1/20 0.35
GAA P10253 1/20 0.35
HPGD P15428 2/20 0.34
LMNA P02545 1/20 0.34
MEN1 O00255 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1879329 1.00 TAAR1 (0.48) TAAR1MAPTKMT2APTGER1PTGER4
O-Xylene SCHEMBL4796657 0.81 TSHR (0.59) TAAR1MAPTKMT2AACHETSHR
SCHEMBL10776504 0.81 MAOB (0.62) TAAR1MAPTKMT2APTGER1PTGER4
SCHEMBL10984027 0.81 TAAR1 (0.47) TAAR1MAPTKMT2APTGER1PTGER4
SCHEMBL9386168 0.81 TAAR1 (0.47) TAAR1MAPTKMT2APTGER1PTGER4
SCHEMBL16167522 0.80 TAAR1 (0.56) TAAR1MAPTKMT2APTGER1PTGER4
SCHEMBL1276610 0.80 TAAR1 (0.56) TAAR1MAPTKMT2APTGER1PTGER4
SCHEMBL6546958 0.79 PTGER4 (0.50) TAAR1KMT2APTGER1PTGER4PTGER3
SCHEMBL9639319 0.79 TAAR1 (0.45) TAAR1MAPTKMT2APTGER1PTGER4
SCHEMBL8463881 0.79 TAAR1 (0.55) TAAR1MAPTKMT2AACHETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100584810-C Preparation method of 1,5-dimethyltetralin using dealuminated zeolite beta catalyst HYOSUNG CORP 2010-01-27 CN claimed
EP-1849758-B1 Preparation method of 1,5-dimethyltetralin using dealuminated zeolite beta catalyst HYOSUNG CORP (KR) 2009-03-25 EP claimed
EP-1849758-A1 Preparation method of 1,5-dimethyltetralin using dealuminated zeolite beta catalyst Hyosung Corporation (KR) 2007-10-31 EP claimed
CN-101050161-A Preparation method of 1,5-dimethyltetralin using dealuminated zeolite beta catalyst HYOSUNG CORP (KR) 2007-10-10 CN claimed
US-20070232842-A1 Preparation method of 1,5-dimethyltetralin using dealuminated zeolite beta catalyst HYOSUNG CORPORATION (KR) 2007-10-04 US claimed
WO-2004058666-A1 PREPARATION METHOD OF 1,5-DIMETHYLTETRALIN HYOSUNG CORPORATION (KR) 2004-07-15 WO claimed
JP-8040946-A None JP disclosed
JP-7033688-A None JP disclosed
JP-6056709-A None JP disclosed
US-7935856-B2 Preparation method of 1,5-dimethyltetralin using dealuminated zeolite beta catalyst HYOSUNG CORPORATION (KR) 2011-05-03 US disclosed
CN-100584810-C Preparation method of 1,5-dimethyltetralin using dealuminated zeolite beta catalyst HYOSUNG CORP 2010-01-27 CN disclosed
EP-1849758-B1 Preparation method of 1,5-dimethyltetralin using dealuminated zeolite beta catalyst HYOSUNG CORP (KR) 2009-03-25 EP disclosed
EP-1849758-A1 Preparation method of 1,5-dimethyltetralin using dealuminated zeolite beta catalyst Hyosung Corporation (KR) 2007-10-31 EP disclosed
US-5329058-A Reacting an alkylbenzene with a conjugated diolefin using a catalyst dispersion TEIJIN LIMIED (JP) 1994-07-12 US disclosed
EP-0594856-A1 PROCESS FOR PRODUCING DIALKYLNAPHTHALENE TEIJIN LIMITED (JP) 1994-05-04 EP disclosed
JP-H0656709-A PRODUCTION OF DIMETHYLTETRALIN MITSUBISHI GAS CHEM CO INC 1994-03-01 JP disclosed
EP-0547336-A1 Process for producing alkenylbenzene TEIJIN LIMITED (JP) 1993-06-23 EP disclosed
US-3997616-A FROM ALKENYLBENZENE, CYCLIZATION CATALYST TEIJIN LIMITED (JA) 1976-12-14 US disclosed
US-3954896-A BOILING ALKYLBENZENE AND CONJUGATED DIENE TEIJIN LIMITED (JA) 1976-05-04 US disclosed
US-3953535-A METALLIC SODIUM AND POTASSIUM CATALYSTS TEIJIN LIMITED (JA) 1976-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070232842-A1 Preparation method of 1,5-dimethyltetralin using dealuminated zeolite beta catalyst DERA, DIMT1, MGST1 TAAR1 893/4885MAPT 3070/4885KMT2A 1466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.