Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 20/20 | 0.72 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20738678 | 0.89 | MAPK1 (0.71) | MAPK1MAPK3 | |
| SCHEMBL18766156 | 0.88 | MAPK1 (0.60) | MAPK1MAPK3 | |
| SCHEMBL18793321 | 0.86 | MAPK1 (0.54) | MAPK1 | |
| SCHEMBL20738628 | 0.85 | MAPK1 (0.54) | MAPK1 | |
| SCHEMBL18765648 | 0.84 | MAPK1 (1.00) | MAPK1MAPK3 | |
| SCHEMBL18765701 | 0.82 | MAPK1 (0.53) | MAPK1 | |
| SCHEMBL18765704 | 0.82 | MAPK1 (0.53) | MAPK1 | |
| SCHEMBL18794012 | 0.80 | MAPK1 (0.49) | MAPK1 | |
| SCHEMBL28764578 | 0.80 | MAPK1 (0.49) | MAPK1 | |
| SCHEMBL18766115 | 0.79 | MAPK1 (0.49) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017068412-A1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2017-04-27 | — | — | WO | disclosed |