Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29345009 | 0.86 | MAPK1 (0.60) | MAPK1 | |
| SCHEMBL29345145 | 0.80 | MAPK1 (0.65) | MAPK1 | |
| SCHEMBL29345046 | 0.79 | MAPK1 (0.83) | MAPK1 | |
| SCHEMBL29343622 | 0.79 | MAPK1 (0.66) | MAPK1 | |
| SCHEMBL29341895 | 0.79 | MAPK1 (0.62) | MAPK1 | |
| SCHEMBL18793450 | 0.78 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL29675795 | 0.78 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL18766157 | 0.78 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL29338685 | 0.77 | MAPK1 (0.56) | MAPK1 | |
| SCHEMBL18793495 | 0.77 | MAPK1 (0.60) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017068412-A1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2017-04-27 | — | — | WO | disclosed |