Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 20/20 | 0.65 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29343631 | 0.85 | MAPK1 (0.63) | MAPK1 | |
| SCHEMBL29341894 | 0.83 | MAPK1 (0.63) | MAPK1MAPK3 | |
| SCHEMBL29343703 | 0.83 | MAPK1 (0.61) | MAPK1MAPK3 | |
| SCHEMBL29345215 | 0.82 | MAPK1 (0.61) | MAPK1MAPK3 | |
| SCHEMBL29343622 | 0.82 | MAPK1 (0.66) | MAPK1 | |
| SCHEMBL18794026 | 0.82 | MAPK1 (0.64) | MAPK1 | |
| SCHEMBL29339878 | 0.82 | MAPK1 (0.58) | MAPK1 | |
| SCHEMBL29343626 | 0.81 | MAPK1 (0.63) | MAPK1 | |
| SCHEMBL18794232 | 0.81 | MAPK1 (0.60) | MAPK1 | |
| SCHEMBL29341864 | 0.81 | MAPK1 (0.61) | MAPK1MAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017068412-A1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2017-04-27 | — | — | WO | disclosed |