SCHEMBL1879544

SCHEMBL1879544

OCc1cc(Br)ccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29961053 1.00
SCHEMBL15526283 0.83 KDM4E (0.42)
SCHEMBL12815077 0.79 KDM4E (0.40)
SCHEMBL2299751 0.79
SCHEMBL29898951 0.79
SCHEMBL23235054 0.77
SCHEMBL510676 0.77
SCHEMBL3196761 0.77
SCHEMBL539467 0.77
SCHEMBL7667910 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 326 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113979955-B Preparation method of heterocyclic ester compound 河南农业大学 2024-05-14 CN claimed
CN-116411037-A Preparation method of azacyclic ester compound 河南农业大学 2023-07-11 CN claimed
CN-113979955-A Preparation method of heterocyclic ester compound 河南农业大学 2022-01-28 CN claimed
CN-108516953-A A kind of synthetic method of 2- pyridine carboxaldehydes derivative 天津全和诚科技有限责任公司 2018-09-11 CN claimed
US-12617797-B2 Substituted pyrazolo [1,5-a]pyrimidines having multimodal activity against pain ESTEVE PHARMACEUTICALS, S.A. (ES) 2026-05-05 US disclosed
WO-2026088070-A1 COMPOUNDS PFIZER INC. (US) 2026-04-30 WO disclosed
US-12606541-B2 PPARg modulators and methods of use EISAI R&D MANAGEMENT CO., LTD. (JP) 2026-04-21 US disclosed
EP-4200299-B1 COMPOUNDS FOR PREVENTION OR TREATMENT OF NEURODEGENERATIVE DISORDERS 1ST BIOTHERAPEUTICS INC (KR) 2026-03-18 EP disclosed
US-12521399-B2 Compound as voltage-gated sodium channel inhibitor GUANGZHOU FERMION TECHNOLOGY CO., LTD. (CN) 2026-01-13 US disclosed
WO-2025215558-A1 COMPOUNDS FOR SPLICING MODULATION FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) 2025-10-16 WO disclosed
US-12441724-B2 Inhibitors of plasma kallikrein and uses thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-10-14 US disclosed
US-12441726-B2 Compounds and uses thereof FOGHORN THERAPEUTICS, INC. (US) 2025-10-14 US disclosed
WO-1995003300-A1 HETEROARYL QUINOLINES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS MERCK FROSST CANADA INC. (CA) 1995-02-02 WO disclosed
US-5360815-A Heteroaryl cinnamic acids as inhibitors of leukotriene biosynthesis MERCK FROSST CANADA, INC. (CA) 1994-11-01 US disclosed
US-5350744-A Antiinflammatory, antiallergen MERCK FROSST CANADA, INC. (CA) 1994-09-27 US disclosed
US-5308852-A Cardiovascular disorders MERCK FROSST CANADA, INC. (CA) 1994-05-03 US disclosed
WO-1994005653-A1 PHENYLNAPHTHALENE HYDROXY ACIDS AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS MERCK FROSST CANADA INC. (CA) 1994-03-17 WO disclosed
WO-1994005656-A1 PHENYLNAPHTHALENE LACTONES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS MERCK FROSST CANADA INC. (CA) 1994-03-17 WO disclosed
EP-0579304-A1 Heteroarylnaphthalenes as inhibitors of leukotriene biosynthesis MERCK FROSST CANADA INC. (CA) 1994-01-19 EP disclosed
WO-1994000444-A1 HETEROARYLNAPHTHALENES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS MERCK FROSST CANADA INC. (CA) 1994-01-06 WO disclosed