SCHEMBL1879665

SCHEMBL1879665

CCCCC=CC(=O)OCc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.59
LMNA P02545 2/20 0.56
MAPT P10636 2/20 0.56
AKR1B10 O60218 2/20 0.52
AKR1B1 P15121 2/20 0.52
CA12 O43570 2/20 0.52
CA4 P22748 2/20 0.52
CA6 P23280 2/20 0.52
CA5A P35218 2/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA14 Q9ULX7 2/20 0.52
CA5B Q9Y2D0 2/20 0.52
ALDH1A1 P00352 5/20 0.51
CYP3A4 P08684 2/20 0.51
TSHR P16473 2/20 0.51
MAPK1 P28482 2/20 0.51
TDP1 Q9NUW8 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
TTR P02766 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29196901 0.94 HCAR2 (0.56) HCAR2LMNAMAPTAKR1B10AKR1B1
SCHEMBL14871736 0.94 HCAR2 (0.56) HCAR2LMNAMAPTAKR1B10AKR1B1
SCHEMBL6656275 0.91 HCAR2 (0.68) HCAR2LMNAMAPTAKR1B10AKR1B1
SCHEMBL6656272 0.91 HCAR2 (0.68) HCAR2LMNAMAPTAKR1B10AKR1B1
SCHEMBL29666406 0.85 HCAR2 (0.52) HCAR2LMNAMAPTAKR1B10AKR1B1
SCHEMBL27694704 0.85 MAPT (0.56) HCAR2LMNAMAPTAKR1B10AKR1B1
SCHEMBL6966475 0.84 HCAR2 (0.54) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL7187261 0.84 HCAR2 (0.67) HCAR2LMNAMAPTAKR1B10AKR1B1
SCHEMBL1879191 0.84 HCAR2 (0.67) HCAR2LMNAMAPTAKR1B10AKR1B1
SCHEMBL3445675 0.83 HCAR2 (0.66) HCAR2LMNAMAPTAKR1B10AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1666440-B1 METHOD FOR PRODUCING AROMATIC UNSATURATED COMPOUND SUMITOMO CHEMICAL CO (JP) 2014-01-22 EP disclosed
US-7939674-B2 Process for producing an aromatic unsaturated compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-05-10 US disclosed
US-7700642-B2 Process for producing an aromatic unsaturated compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-20 US disclosed
US-20090111999-A1 PROCESS FOR PRODUCING AN AROMATIC UNSATURATED COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-04-30 US disclosed
US-20080221337-A1 Process for Producing an Aromatic Unsaturated Compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-11 US disclosed
EP-1666440-A1 METHOD FOR PRODUCING AROMATIC UNSATURATED COMPOUND Sumitomo Chemical Company, Limited (JP) 2006-06-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080221337-A1 Process for Producing an Aromatic Unsaturated Compound AHR, AR, ARSA HCAR2 122/4885LMNA 788/4885MAPT 4307/4885
US-20090111999-A1 PROCESS FOR PRODUCING AN AROMATIC UNSATURATED COMPOUND AHR, AR, ARSA HCAR2 122/4885LMNA 788/4885MAPT 4307/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.