Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16921310 | 0.94 | TRPV1 (0.58) | TRPV1GAAHPGDL3MBTL1LMNA | |
| SCHEMBL18798870 | 0.93 | TRPV1 (0.56) | TRPV1GAAHPGDL3MBTL1LMNA | |
| SCHEMBL16921283 | 0.92 | TRPV1 (0.62) | TRPV1GAAHPGDL3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL16909120 | 0.91 | TRPV1 (0.61) | TRPV1GAAHPGDL3MBTL1LMNA | |
| SCHEMBL18798901 | 0.91 | TRPV1 (0.53) | TRPV1GAAHPGDL3MBTL1LMNA | |
| SCHEMBL16909102 | 0.90 | TRPV1 (0.55) | TRPV1GAAHPGDL3MBTL1LMNA | |
| SCHEMBL18798805 | 0.90 | TRPV1 (0.52) | TRPV1GAAHPGDL3MBTL1LMNA | |
| SCHEMBL16909235 | 0.89 | TRPV1 (0.51) | TRPV1GAAHPGDL3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL16909083 | 0.88 | TRPV1 (0.50) | TRPV1GAAHPGDL3MBTL1LMNA | |
| SCHEMBL16909176 | 0.87 | GAA (0.55) | TRPV1GAAHPGDL3MBTL1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9636298-B2 | Prodrugs of compounds that enhance antifungal activity and compositions of said prodrugs | METHYLGENE INC (CA) | 2017-05-02 | — | — | US | disclosed |