Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | RHEB | Q15382 | 1/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29613191 | 0.81 | GAA (0.53) | MAPTTP53GAAPOLBLMNA | |
| SCHEMBL9394915 | 0.81 | GAA (0.53) | MAPTTP53GAAPOLBLMNA | |
| SCHEMBL27250286 | 0.78 | HDAC1 (0.40) | MAPTPOLBLMNAKDM4E | |
| SCHEMBL20292730 | 0.74 | GAA (0.56) | MAPTTP53GAALMNABRD4 | |
| SCHEMBL15957895 | 0.73 | TP53 (0.55) | MAPTTP53GAAPOLBLMNA | |
| SCHEMBL13833580 | 0.72 | GAA (0.57) | MAPTTP53GAAPOLBLMNA | |
| SCHEMBL23951522 | 0.71 | GAA (0.53) | MAPTTP53GAAPOLBLMNA | |
| SCHEMBL18368374 | 0.71 | GAA (0.53) | MAPTTP53GAAPOLBLMNA | |
| SCHEMBL15519326 | 0.70 | GAA (0.56) | MAPTTP53GAALMNABRD4 | |
| SCHEMBL5140683 | 0.70 | GAA (0.56) | MAPTTP53GAALMNABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9636375-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-05-02 | — | — | US | disclosed |