Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 4/20 | 0.52 |
| ▸ | TAOK1 | Q7L7X3 | 4/20 | 0.50 |
| ▸ | TAOK3 | Q9H2K8 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18337978 | 1.00 | XIAP (0.52) | XIAPTAOK1TAOK3L3MBTL1KMT2A | |
| SCHEMBL16392446 | 1.00 | XIAP (0.52) | XIAPTAOK1TAOK3L3MBTL1KMT2A | |
| SCHEMBL18337854 | 0.86 | XIAP (0.56) | XIAPTAOK1TAOK3L3MBTL1KMT2A | |
| SCHEMBL18799816 | 0.86 | XIAP (0.69) | XIAP | |
| SCHEMBL16392442 | 0.86 | XIAP (0.56) | XIAPTAOK1TAOK3L3MBTL1KMT2A | |
| SCHEMBL16392432 | 0.86 | XIAP (0.69) | XIAP | |
| Hydrochloric Acid SCHEMBL18338007 | 0.86 | XIAP (0.53) | XIAPTAOK1TAOK3KMT2AMEN1 | |
| SCHEMBL16392362 | 0.85 | XIAP (0.56) | XIAPTAOK1TAOK3L3MBTL1KMT2A | |
| SCHEMBL16370583 | 0.84 | KMT2A (0.55) | TAOK1TAOK3L3MBTL1KMT2AMEN1 | |
| SCHEMBL16371380 | 0.84 | KMT2A (0.55) | TAOK1TAOK3L3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9637518-B2 | IAP antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-05-02 | — | — | US | disclosed |