Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 5/20 | 0.44 |
| ▸ | CES1 | P23141 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 6/20 | 0.39 |
| ▸ | PPARD | Q03181 | 6/20 | 0.39 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896875 | 0.98 | KMT2A (0.54) | KMT2AMAPTCES2CES1ALDH1A1 | |
| SCHEMBL8896880 | 0.93 | KMT2A (0.59) | KMT2AMAPTCES2CES1ALDH1A1 | |
| SCHEMBL8896816 | 0.93 | KMT2A (0.59) | KMT2AMAPTCES2CES1ALDH1A1 | |
| SCHEMBL28332249 | 0.93 | MAPT (0.46) | KMT2AMAPTCES2CES1ALDH1A1 | |
| SCHEMBL15457429 | 0.91 | MAPT (0.41) | KMT2AMAPTCES2CES1ALDH1A1 | |
| SCHEMBL8896912 | 0.89 | KMT2A (0.48) | KMT2AMAPTCES2CES1ALDH1A1 | |
| SCHEMBL8896005 | 0.89 | KMT2A (0.59) | KMT2AMAPTCES2CES1ALDH1A1 | |
| SCHEMBL15457430 | 0.88 | KMT2A (0.44) | KMT2AMAPTCES2CES1ALDH1A1 | |
| SCHEMBL491385 | 0.86 | KMT2A (0.56) | KMT2AMAPTCES2CES1ALDH1A1 | |
| SCHEMBL25885737 | 0.85 | MAPT (0.41) | KMT2AMAPTCES2CES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9636670-B2 | Catalysts, ligands and use thereof | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2017-05-02 | — | — | US | disclosed |
| US-9627217-B2 | Silicon-containing EUV resist underlayer film-forming composition including additive | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-04-18 | — | — | US | disclosed |
| US-20150079792-A1 | SILICON-CONTAINING EUV RESIST UNDERLAYER FILM-FORMING COMPOSITION INCLUDING ADDITIVE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-03-19 | — | — | US | disclosed |