Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 20/20 | 0.61 |
| ▸ | EZH1 | Q92800 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12499510 | 0.89 | EZH2 (0.78) | EZH2EZH1 | |
| SCHEMBL20170249 | 0.87 | EZH2 (0.59) | EZH2EZH1 | |
| SCHEMBL25543956 | 0.83 | EZH2 (0.51) | EZH2EZH1 | |
| SCHEMBL29357504 | 0.79 | EZH2 (0.78) | EZH2EZH1 | |
| SCHEMBL12684069 | 0.79 | EZH2 (0.78) | EZH2EZH1 | |
| SCHEMBL20170343 | 0.78 | EZH2 (0.63) | EZH2EZH1 | |
| SCHEMBL19958911 | 0.77 | EZH2 (0.53) | EZH2 | |
| SCHEMBL19657083 | 0.77 | EZH2 (0.59) | EZH2EZH1 | |
| SCHEMBL12499470 | 0.76 | EZH2 (1.00) | EZH2EZH1 | |
| SCHEMBL12499081 | 0.76 | EZH2 (0.66) | EZH2EZH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9637472-B2 | Substituted 6,5-fused bicyclic heteroaryl compounds | Epizyme, Inc. (US) | 2017-05-02 | — | — | US | disclosed |